abstract：:The carriage on skin lesions, on healthy skin and in the nose, of micro-organisms that produce antibiotics active against Staphylococcus aureus has been studied. About 5% of sites (10% of all patients) yielded such organisms. No evidence could be found that the presence of producer organisms in skin lesions had a prot...

journal_title：Journal of medical microbiology

authors： Noble WC,Willie JA

更新日期：1980-05-01 00:00:00

abstract：:Intestinal absorption of arbutin (p-hydroxyphenyl-beta-glucoside), a non-metabolised analogue of d-glucose, and net flux of water out of the small intestinal lumen were found to be decreased in vitro in rats fed with Candida albicans. In rats on a protein-deficient diet and fed C. albicans there was net secretion of w...

journal_title：Journal of medical microbiology

authors： Burke V,Gracey M

更新日期：1980-02-01 00:00:00

abstract：:Electronmicrographs of sections show that the L-phases of Bacillus licheniformis var. endoparasiticus (Benedek) simulate the various types of micro-organism described by previous workers as associated with ostensibly noninfective conditions, notably cancer and arthritis; e.g., mycoplasmas, mycobacteria, corynebacteria...

journal_title：Journal of medical microbiology

authors： Bisset KA,Tallack J,Bartlett R

更新日期：1979-11-01 00:00:00

abstract：:Inhibitors of trophozoite motility and phagocytosis were used to investigate the mechanism of Naegleria fowleri cytopathogenicity in mouse-embryo (ME)-cell cultures. Amoebae that were immobilised and agglutinated by specific antiserum exhibited no cytopathic activity, although they remained alive and were in constant ...

journal_title：Journal of medical microbiology

authors： Brown T

更新日期：1979-08-01 00:00:00

abstract：:A strain of Staphylococcus aureus (M7) contains a transmissible element determining production of penicillinase, and resistance to cadmium ions, neomycin, streptomycin and kanamycin (CPNS). This element was transferred either in toto or in fragments at low frequency from strain M7. The fragment (NS) possesses features...

journal_title：Journal of medical microbiology

authors： Lacey RW

更新日期：1979-08-01 00:00:00

abstract：:Thirty-six closed abcesses in the subcutis of cats were examined. Of 168 bacterial strains isolated, 121(72%) were anaerobes and 47 (28%) were facultative anaerobes. Twenty-six abscesses contained mixtures of facultative anaerobes and anaerobes, six contained anaerobes only and four contained facultative anaerobes onl...

journal_title：Journal of medical microbiology

authors： Love DN,Jones RF,Bailey M,Johnson RS

更新日期：1979-05-01 00:00:00

abstract：:The acquisition of Klebsiella aerogenes by neonates born in hospital has been studied by sero- and klebecin typing. This organism was more commonly carried in the bowel of breast-fed babies than of bottle-fed babies. Only very rarely did babies acquire strains of K. aerogenes from their mothers. K. aerogenes was widel...

journal_title：Journal of medical microbiology

authors： Shinebaum R,Cooke EM,Brayson JC

更新日期：1979-05-01 00:00:00

abstract：:The strains of Proteus species found in significant numbers and as pure cultures in urine from 217 individuals were isolated, identified to species level and typed for proticine production (P type) and proticine sensitivity (S type) to give their P/S type. Urinary-tract infections with Proteus, principally P. mirabili...

journal_title：Journal of medical microbiology

authors： Senior BW

更新日期：1979-02-01 00:00:00

abstract：:A rapid and simple method for counting viable bacteria is described. The technique involves the use of a semi-automatic micropipette and disposable glass-capillary tubes. Viable counts obtained by this method were not significantly different from those obtained by the Miles, Misra and Irwin method or by a pour-plate m...

journal_title：Journal of medical microbiology

authors： Slack MP,Wheldon DB

更新日期：1978-11-01 00:00:00

abstract：:Small round viruses (SRV) were isolated from the faeces of diarrhoeic calves from three farms. All three SRV preparations caused diarrhoea experimentally in gnotobiotic calves. Each preparation contained viral particles of two morphological types, "astrovirus-like" and "calicivirus-like", and from one preparation the ...

journal_title：Journal of medical microbiology

authors： Woode GN,Bridger JC

更新日期：1978-11-01 00:00:00

abstract：:A rabbit was immunised with a heat-killed vaccine prepared from strain 1142 of Staphylococcus epidermidis. The HA titres of the antisera against a surface-polysaccharide antigen extracted from the homologous strain were highest in the 2nd-4th weeks after immunisation and subsequently declined. Only a minor amount of 2...

journal_title：Journal of medical microbiology

authors： Yoshida K,Ichiman Y

更新日期：1978-11-01 00:00:00

abstract：:The microtechnique of Galton et al. (1965) for the routine screening of blood samples for leptospiral antibodies was used to examine more than 8000 serum samples from animals that had aborted and from herds in which leptospiral antibodies had previously been demonstrated. The method gave consistently accurate results....

journal_title：Journal of medical microbiology

authors： Lewis J

更新日期：1978-08-01 00:00:00

abstract：:A serial study of rotavirus infection in gnotobiotic piglets is described. They were infected when 7 days old and the course of infection was followed for 21 days, by immunofluorescence and histological examinations of the intestinal epithelium and by titration of the virus content of the gut lumen. There appeared to ...

journal_title：Journal of medical microbiology

authors： Crouch CF,Woode GN

更新日期：1978-08-01 00:00:00

abstract：:Preliminary differentiation of Leptospira interrogans serovars hardjo and balcanica can be made with antisera that are collected from hamsters after experimental infection with serovar hardjo and selected for high homologous and low or nil heterologous titres, as measured by the microscopic agglutination test. Rabbit ...

journal_title：Journal of medical microbiology

authors： Ris DR,Hamel KL

更新日期：1978-08-01 00:00:00

abstract：:The adhesion of bovine and a human isolate of Escherichia coli to epithelial cells from the teat and lactiferous sinuses of the udder was examined. Adhesion was detected with bacterial suspensions that produced mannose-sensitive agglutination of guinea-pig red cells. Adhesion to epithelial cells could be inhibited by ...

journal_title：Journal of medical microbiology

authors： Harper M,Turvey A,Bramley AJ

更新日期：1978-05-01 00:00:00

abstract：:The acid end-products of 185 isolates from the family Bacteroidaceae were separated and analysed by gas-liquid chromatography on broth cultures. Different media were evaluated and definitive studies were performed in a fully supplemented complex medium. The limitations of this approach to the identification of a wide ...

journal_title：Journal of medical microbiology

authors： Deacon AG,Duerden BI,Holbrook WP

更新日期：1978-05-01 00:00:00

abstract：:Breast-fed infants are less susceptible to gastroenteritis than bottle-fed infants. Antibodies against rotavirus, the major pathogen of infantile gastroenteritis, were sought in human sera, colostrum and milk specimens by immunofluorescence. An experimental murine-rotavirus model was established by infecting the secon...

journal_title：Journal of medical microbiology

authors： Schoub BD,Prozesky OW,Lecatsas G,Oosthuizen R

更新日期：1978-02-01 00:00:00

abstract：:A solid-phase radioimmunoassay was used to detect IgG antibodies against herpes-simplex virus antigens (capsid, envelope and excreted) and against measles virus antigen in serum and cerebrospinal fluid (CSF) specimens of 61 patients with no evidence of infectious or demyelinating disease of the central nervous system....

journal_title：Journal of medical microbiology

authors： Kalimo KO,Marttila RJ,Ziola BR,Matikainen MT,Panelius M

更新日期：1977-11-01 00:00:00

abstract：:The activities of three sulphonamides and trimethoprim against strains of Pseudomonas aeruginosa have been studied. Sulphadiazine had most activity, sulphadimidine had little, and the activity of sulphamethoxazole was intermediate. According to their sensitivity to sulphamethoxazole, strains were divided into two grou...

journal_title：Journal of medical microbiology

authors： Grey D,Hamilton-Miller JM

更新日期：1977-08-01 00:00:00

abstract：:During a 3-year period, 771 rectal swabs were taken from abacteriuric school-children. Out of 709 E. coli strains, each isolated from one faecal specimen, 102 were found to be resistant to one or more antibacterial agents, and 607 to be fully sensitive. Another 204 resistant strains were found by selection for antibio...

journal_title：Journal of medical microbiology

authors： Lidin-Janson G,Falsen E,Jodal U,Kaijser B,Lincoln K

更新日期：1977-08-01 00:00:00

abstract：:Certain bile acids inhibit the growth in vitro of organisms commonly found in the intestine and, in particular, anaerobic bacteria. As the importance of this effect in vivo has not been demonstrated, we investigated changes in intestinal flora in the rat after diversion of bile to the urinary bladder. Five days after ...

journal_title：Journal of medical microbiology

authors： Burke V,Stone DE,Beaman J,Gracey M

更新日期：1977-05-01 00:00:00

abstract：:In tests of bactericidal action against H. influenzae type b strains isolated from patients with meningitis, chloramphenicol was found to be far more reliable than ampicillin in dealing with large inocula, and more rapidly effective against both large and relatively small inocula. These findings provide a laboratory e...

journal_title：Journal of medical microbiology

authors： Turk DC

更新日期：1977-02-01 00:00:00

abstract：:Simulated throat swabs were prepared with known numbers of Streptococcus pyogenes; some were suspended in pasteurised human saliva and an equal number in saline. Two types of commercially available swabs were tested; these were composed of (1) plain, buffered, cotton wool, and (2) albumen-coated cotton wool. The mean ...

journal_title：Journal of medical microbiology

authors： Ross PW

更新日期：1977-02-01 00:00:00

abstract：:Leucocyte-egested material was harvested after the quantitative in-vitro phagocytosis of Neisseria meningitidis by rabbit or mouse polymorphonuclear leucocytes. The egested material was injected subcutaneously into rabbits and followed 24 h later with an intravenous injection of what would by itself have been a non-le...

journal_title：Journal of medical microbiology

authors： DeVoe IW,Gilka F

更新日期：1976-11-01 00:00:00

abstract：:A collection of 820 isolates of streptococci and aerococci from human blood or internal organs was classified by means of a set of cultural and biochemical tests. Of these, 719 (712 streptococci and 7 aerococci) were from patients believed to be suffering from a systemic infection: endocarditis 317; a purulent lesion ...

journal_title：Journal of medical microbiology

authors： Parker MT,Ball LC

更新日期：1976-08-01 00:00:00

abstract：:Fifty-seven strains of acinetobacter-like organisms were isolated over a period of 26 months from the ears of 55 patients with acute or chronic otitis media, or otitis externa, and one strain was isolated in a survey of 50 normal ears. After comparison with eight reference strains, 32 of the isolates were identified a...

journal_title：Journal of medical microbiology

authors： Dadswell JV

更新日期：1976-08-01 00:00:00

abstract：:Tests with 140 strains representing Escherichia coli, Klebsiella aerogenes, K. ozaenae, Proteus mirabilis, P. vulgaris, P. rettgeri and P. morganii in a defined medium supplemented with 0-09M dimethylamine (DMA) and 0-1M potassium nitrate showed that at least 89% of the 136 strains able to reduce nitrates produced up ...

journal_title：Journal of medical microbiology

authors： Coloe PJ,Hayward NJ

更新日期：1976-05-01 00:00:00

abstract：:Five Bordetella pertussis strains of phase I were grown in conventional casamino-acid medium and in media modified by adding high concentrations of MgSO4 or nicotinic acid. Cells grown in high-magnesium media (in the C-mode) had only about 4% of the protective antigen (PA) and 6% of the histamine-sensitising factor (H...

journal_title：Journal of medical microbiology

authors： Wardlaw AC,Parton R,Hooker MJ

更新日期：1976-02-01 00:00:00

abstract：:Various factors influencing the susceptibility of C3H mice to lethal infection by the phycomycete Absidia ramosa were examined. Mice 19-21 days old were exposed to graded doses of A. ramosa spores by various routes. After intravenous inoculation with doses in excess of 10(3) viable units, a variable proportion of mice...

journal_title：Journal of medical microbiology

authors： Corbel MJ,Eades SM

更新日期：1975-11-01 00:00:00

abstract：:A provisional serotyping scheme for Bacillus cereus has been developed. Eighteen selected cultures of B. cereus isolated from foods and clinical specimens were used to prepare agglutinating sera against the flagellar antigen. There were no significant cross-reactions between the sera. The sera were used to type 137 is...

journal_title：Journal of medical microbiology

authors： Taylor AJ,Gilbert RJ

更新日期：1975-11-01 00:00:00

abstract：:Production of beta-lactamase by 15 strains of Haemophilus influenzae has been investigated. All the strains produce a constitutive beta-lactamase, which readily hydrolyses penicillin G, ampicillin, and cephaloridine. The beta-lactamase produced by these strains is indistinguishable from the type-IIIa enzyme commonly f...

journal_title：Journal of medical microbiology

authors： Sykes RB,Matthew M,O'Callaghan CH

更新日期：1975-08-01 00:00:00

abstract：:The growth of 29 strains of Acinetobacter spp. on semi-solid media was studied; 19 showed surface swarming and 14 produced channels ("ditches") in the agar that do not seem to have been described previously. An attempt was made to define the cultural and physical conditions for the demonstration of these phenomena. Po...

journal_title：Journal of medical microbiology

authors： Barker J,Maxted H

更新日期：1975-08-01 00:00:00

abstract：:A simple method is described for testing milk specimens from nursing mothers for the presence of RNA-dependent DNA-polymerase activity. Positive results were obtained in five of 137 women (3.6%) without a family history of breast cancer, and in six of 31 women (19.3%) with a family history of breast cancer. ...

journal_title：Journal of medical microbiology

authors： McFarlane ES,Ryan SM,Mann E

更新日期：1975-08-01 00:00:00

abstract：:Shanson's medium, a MacConkey-type agar containing added inhibitors, was compared with deoxycholate-citrate agar for the examination of faeces. The isolation rate of samonellae on the two media was similar, but Shanson's medium was the more selective; this meant that the amount of work required to produce a result was...

journal_title：Journal of medical microbiology

authors： Davies JR

更新日期：1975-05-01 00:00:00

abstract：:Staphylococcus aureus strains were treated with ethylmethane sulphonate with the object of obtaining mutants that differed from the wild type in one of the properties that might contribute to virulence. Mutants with isolated loss or deficient production of gamma-haemolysin, coagulase, leucocidin and staphylokinase wer...

journal_title：Journal of medical microbiology

authors： van der Vijver JC,van Es-Boon MM,Michel MF

更新日期：1975-05-01 00:00:00

abstract：:Erythrocyte-sensitising antigens (AE) were prepared from Vibrio cholerae serotypes, from EL-Tor vibrio, Escherichia coli and Salmonella enteritidis by digesting the organisms with NaOH followed by precipitation with alcohol. When AE was used in indirect haemagglutination (IHA) tests, the results in a number of cases w...

journal_title：Journal of medical microbiology

authors： Garabedian GA,Barsumian EL,Malakian A

更新日期：1975-02-01 00:00:00

abstract：:Immunodiffusion analysis of Mycobacterium lepraemurium indicated the presence of at lease six antigens. Comparative analysis of the M. lepraemurium antigen-antibody system with similar systems established for other mycobacterial species, showed that M. lepraemurium shared up to two antigens with other species. Althoug...

journal_title：Journal of medical microbiology

authors： Navalkar RG,Dalvi RR,Patel PJ

更新日期：1975-02-01 00:00:00

abstract：:Alpha protoxin of Staphylococcus aureus "Wood 46" was activated by trypsin which had been coupled to carboxymethylcellulose, as indicated by the toxin's ability to hydrolyse tosyl-arginine methylester (TAME). A Lineweaver-Burk plot of the degradation of TAME by toxin and trypsin showed that toxin had a greater affinit...

journal_title：Journal of medical microbiology

authors： Wiseman GM,Caird JD,Fackrell HB

更新日期：1975-02-01 00:00:00

abstract：:The possession of any of eight different plasmids by Staphylococcus aureus strain 649--either singly or simultaneously (in no. 649MR)--caused changes in growth kinetics. Six of the plasmids caused an increase in exponential doubling time (by 8-25%), and most also altered the duration of the lag period. Strain 649MR wa...

journal_title：Journal of medical microbiology

authors： Lacey RW,Chopra I

更新日期：1975-02-01 00:00:00

abstract：:Bacterial activity and growth were monitored by following the changes of electrical impedance of cultures in liquid media. The signal is expressed automatically as a curve similar to grwoth curves produced by other methods. The technique offers a new, rapid and sensitive means of detecting active micro-organisms and i...

journal_title：Journal of medical microbiology

authors： Ur A,Brown DF

更新日期：1975-02-01 00:00:00